The mechanism of zocor
As you now know from the post what is zocor, zocor is a cholesterol lowering drug.
Cholesterol in our body is a result of the fat we eat from food and the fat our body produces. We have 2 types of cholesterol; LDL (also called “bad cholesterol”) and HDL (the “good cholesterol”).
LDL form aggregates on the wall of the arteries. Doing so the arteries diameter is narrowed and as a result there is a slow or blocked blood flow. So LDL cholesterol is the main cause of heart disease or stroke.
The biosynthesis of cholesterol is a complex process. At one step HMG-CoA is converted to mevalonate. The reaction is made possible by the “HMG-CoA reductase” enzyme. Zocor inhibits this enzyme, thus preventing the synthesis of cholesterol.